WEIJUN QIAN
SEEK ID: https://emsl-seek.pnnl.gov/people/51
Location:
United States
ORCID:
https://orcid.org/0000-0002-5393-2827
Joined: 27th Jul 2022
Expertise: Not specified
Tools: Not specified
Their tagsRelated items
A major aim of cancer systems biology is to build models that can predict the impact of these genetic disruptions to guide therapeutic interventions. A prominent driver of cancer cell growth is signaling pathway deregulation from mutations in key regulatory nodes and loss/gain in gene copy number (CNV). Recent work by our group discovered that the abundances of most signaling pathway proteins are highly conserved with signaling being controlled by only a few, low abundance key nodes. The activity ...
Public web page: https://csbconsortium.org/research-projects/reverse-sensitivity-analysis-for-identifying-predictive-proteomics-signatures-of-cancer/
Start date: 1st Apr 2019
End date: 30th Apr 2024
Poster presented at the 2019 annual CSBC meeting: A major aim of cancer systems biology is to build models that can predict the impact of these genetic disruptions to guide therapeutic interventions. A prominent driver of cancer cell growth is signaling pathway deregulation from mutations in key regulatory nodes and loss/gain in gene copy number (CNV). Recent work by our group discovered that the abundances of most signaling pathway proteins are highly conserved with signaling being controlled ...
Creators: Steven Wiley, Herbert Sauro, Becky Hess, WEIJUN QIAN
Submitter: Steven Wiley
